Chemotherapy or hormone therapy will sometimes be the first treatment. Breast cancer is the most prevalent malignancy among women in the Western industrialized world. Therefore, therapeutic decisions should be made using well-accepted prognostic and predictive indicators. CrossRef Google Scholar. You might have it as a treatement for a number of different types of cancer.
These may affect the way the chemotherapy drugs work. Your hospital doctor, specialist nurse or GP can refer you to a counsellor. Apoptosis is one of the most important mechanisms of chemotherapy-induced cytotoxicity. Discuss with your doctor your risk of permanent menopause and its consequences. Another advantage of neoadjuvant chemotherapy is the possibility of breast-conserving surgery in selected patients with LABC [ 48 ].
When, where and how you have chemotherapy | Breast cancer | Cancer Research UK
If the cancer has recurred or spread, chemotherapy may control the breast cancer to help you live longer. J Clin Oncol ; 15 : In contrast, the taxanes induce cell death in a Pindependent manner. At the time this study was conducted, the standard of care for these patients was a modified radical mastectomy. It is a treatment for a number of different types of cancer. Proc Am Assoc Cancer Res ; 39 : a.
Postoperative chemotherapy and tamoxifen compared with tamoxifen alone in the treatment of positive-node breast cancer patients aged 50 years and older with tumors responsive to tamoxifen: results from the National Surgical Adjuvant Breast and Bowel Project B There are a number of chemotherapy drugs used to treat breast cancer. Depending on your age, chemotherapy may induce a premature permanent menopause. Am J Pathol ; : Recently, the use of neoadjuvant chemotherapy has been extended to patients with resectable tumors.